Deidre Littler is the daughter of Renee and Reuben Littler. She lives in Bridgeport's hill area with her family and Odine Perry, who is said to be the family's live-in nanny. She is best friends with Odine Perry, but enemies with her father. Perhaps this is because she discovered about his affair with Odine. She is also enemies with her older brother Bronson and the newspaper delivery girl Seraphina Prattle. She is friends with her mother.
She is unaware of the existence of her half-sister Tiara Angelista, the daughter of her father and Lala Angelista, who was his previous girlfriend. She appears to be talented and intelligent seeing as she has 5 skill points in logic and 4 skill points in writing. She is one of the few Sims to have freckles. Some others are Claire Ursine, Darlene Bunch and Tiara Angelista. Because she and her half-sister Tiara are among the few Sims to have freckles, it could be a recessive genetic trait on her father's side.